Back to top
September 30, 2015

What is Human Growth Hormone (hGH)

James Jemieson and Dr. L.E. Dorman with Valerie Marriott
(information extracted from GROWTH HORMONE: Reversing Human Aging Naturally (The Methuselah Factor ) , written by James Jemieson and Dr. L.E. Dorman with Valerie Marriott)

Human Growth Hormone is one of many endocrine hormones, like estrogen, progesterone, testosterone, melatonin and DHEA, which decline with age. While many of these hormones can be replaced to deter some of the effects of aging, hGH reaches far beyond the scope of any one of these hormones to not only prevent biological aging, but to significantly reverse a broad range of the signs and symptoms associated with aging. In effect, hGH therapy has been shown to turn back the biological clock by 20 years or more!

hGH is the most abundant hormone secreted by the pituitary gland. It is produced at a rate that peaks during adolescence when accelerated growth occurs. Daily growth hormone secretion diminishes with age to the extent that a 60-year-old may secrete 25% of the hGH secreted by a 20-year-old. Growth hormone is primarily released in pulses that take place during the beginning phases of sleep, then it is quickly converted in the liver to its powerful growth promoting metabolite, Insulin-like Growth Factor type 1 (IGF-1.) IGF-1 elicits most of the effects associated with growth hormone and is measured in the blood to determine the level of growth hormone secretion. IGF-1 promotes glucose transfer through cell membranes as a source of fuel for cells, which is an insulin-like effect. Thus the term IGF-1, or insulin-like growth factor. Most of the beneficial effects of hGH are directly associated with IGF-1.

The decline of growth hormone with age, sometimes referred to as somatapause, is directly associated with many of the symptoms of aging, including wrinkles, gray hair, decreased energy and sexual function, increased body fat and cardiovascular disease, osteoporosis, and more. Many of these symptoms have been associated with younger adults who have growth hormone deficiency; in a sense, the biological age of these people has surpassed the chronological age. The good news is that clinical evidence demonstrates that by replacing growth hormone we can dramatically reverse these symptoms to restore hair color and growth, regain bone tissue, increase energy and significantly reduce body fat.

Why do hGH levels decline with age? Researchers have examined the evidence and some theories suggest that the effects of changes in GH regulating hormones like somatostatin and growth hormone releasing hormone (GHRH) account for GH decline. The encouraging evidence is that the aging pituitary maintains the ability to release growth hormone, if it is properly stimulated to do so. Proper diet, exercise, and secretagogues, when used correctly, allow the pituitary to significantly increase levels of growth hormone. Secretagogues are substances on the cutting edge of scientific research that stimulate the pituitary to secrete growth hormone.

Until recently, growth hormone therapy has only been available in the form of injections that have been prohibitively expensive and difficult to use. Now, there are natural substances that have been well documented to stimulate growth hormone in a way that may that may exceed the effectiveness of injections or compliment injection therapy. According to researchers, these cutting edge natural secretagogues may have the ability to more closely mimic the body's youthful GH secretion patterns than any other therapies previously available.

For additional information on this remarkable category of supplements and to view our current selection of state-of-the-art hGH products, visit our Human Growth Hormone (hGH) Page.